141375-47-5 Usage
Uses
Used in Pharmaceutical Industry:
3,5-DIBROMO-4-PYRIDINOL is utilized as an intermediate in the synthesis of pharmaceuticals, playing a crucial role in the development of new drugs. Its unique structure and reactivity allow it to be incorporated into a variety of medicinal compounds, contributing to the advancement of treatments for various health conditions.
Used in Pesticide Production:
In the agrochemical sector, 3,5-DIBROMO-4-PYRIDINOL serves as an intermediate, facilitating the creation of pesticides. Its involvement in this process is instrumental in enhancing crop protection strategies, thereby ensuring increased agricultural productivity and food security.
Used in Organic Compounds Synthesis:
3,5-DIBROMO-4-PYRIDINOL is also employed as a building block in the synthesis of other organic compounds. Its functional groups and reactivity make it an indispensable component in the organic chemistry toolkit, enabling the construction of a wide array of chemical entities for diverse applications.
Used in Research Applications:
Due to its unique properties, 3,5-DIBROMO-4-PYRIDINOL is a valuable asset in research settings. It is used to explore new chemical reactions, investigate the mechanisms of organic processes, and develop innovative methodologies in synthetic chemistry. This contributes to the expansion of scientific knowledge and the discovery of novel applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 141375-47-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,1,3,7 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 141375-47:
(8*1)+(7*4)+(6*1)+(5*3)+(4*7)+(3*5)+(2*4)+(1*7)=115
115 % 10 = 5
So 141375-47-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3Br2NO/c6-3-1-8-2-4(7)5(3)9/h1-2H,(H,8,9)
141375-47-5Relevant articles and documents
Rate-Determining Steps in Michael-Type Additions and E1cb Reactions in Aqueous Solution
Heo, Christina K. M.,Bunting, John W.
, p. 3570 - 3578 (2007/10/02)
Rates of equilibration of a series of 10 substituted pyridines and five Michael acceptors (CH2=CHZ, Z = CHO, COCH3, SO2CH3, CN and CONH2) with the corresponding N(ZCH2CH2) pyridinium cations have been measured in aqueous solution at ionic strength 0.1 and 25 deg C.Analysis of the dependence of the pseudo-first-order rate constants for equilibration as a function of acceptor concentration and of pH allows the evaluation of the second-order rate constants (kNu) for the nucleophilic attack of each of these pyridines upon each of these acceptors and also the second-order rate constants (kOH) for the hydroxide ion catalyzed E1cb elimination reaction which is the microscopic reverse of each of these Michael-type addition reactions.Broensted-type plots for each of these processes as a function of the basicity of the substituted pyridine are concave down for each of Z = CHO, COCH3, and CN and are consistent with a change from rate-determining nucleophilic attack for the more basic pyridines to rate-determining protonation of the carbanionic intermediate by a water molecule for less basic pyridines and the corresponding microscopic reverse processes in the elimination reactions.The "break" in these Broensted-type plots is shown to occur at a pyridine basicity that is a function of the Z-activating substituent.Broensted β1g and βnuc are evaluated for each rate-determining step (wherever accessible); these two parameters are shown to pass through minima as a function of reactivity. βeq is shown to be a simple linear function of reactivity (as log kNu) for nucleophilic addition to the acceptor species, although Keq is relatively insensitive to the nature of the Z-activating substituent.
