The Thorpe-Ziegler-type reaction of 3-cyanopyridine-2(1H)-thiones with Biginelli 6-bromomethyl-3,4-dihydropyrimidin-2(1H)-ones: Cascade assembling of tetra- and pentacyclic heterocyclic scaffolds
3-Cyanopyridine-2(1H)-thiones have been shown to react with Biginelli-type ethyl 4-aryl-6-(bromomethyl)-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates upon heating in DMF giving rise to ethyl 4-aryl-6-{[(3-cyanopyridin-2-yl)thio] methyl}-2-oxo-1,2,3,4-
Lebedyeva, Iryna O.,Povstyanoy, V'Yacheslav M.,Povstyanoy, Mikhaylo V.,Dotsenko, Victor V.,Krivokolysko, Sergey G.,Turovtsev, Vladimir V.
p. 9729 - 9737,9
(2020/08/20)
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