Enabling Wittig reaction on site-specific protein modification
An efficient aqueous Wittig reaction was enabled on protein bioconjugation for the first time. By investigating the reaction on small molecules, peptides, and proteins, a site-specific reaction targeting aldehyde tag was presented. A variety of functional groups could be introduced into the protein of interest.
Han, Ming-Jie,Xiong, De-Cai,Ye, Xin-Shan
supporting information
p. 11079 - 11081
(2013/01/15)
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