141724-22-3Relevant articles and documents
Novel inhibitors of prolyl 4-hydroxylase. 3. Inhibition by the substrate analogue N-oxaloglycine and its derivatives
Cunliffe,Franklin,Hales,Hill
, p. 2652 - 2658 (2007/10/02)
N-Oxaloglycine (3) is an α-ketoglutarate (1) analogue that is a competitive inhibitor of prolyl 4-hydroxylase (EC 1.14.11.2). A study of the structure-activity relationships of some other oxalo derivatives shows that substitution on the glycine moiety mod