1419075-84-5

Basic information

• Product Name: 2-Chloro-4-broMo-5-(trifluoroMethoxy)-benzoic acid
• Synonyms: 4-BROMO-2-CHLORO-5-(TRIFLUOROMETHOXY)BENZOIC ACID;2-Chloro-4-broMo-5-(trifluoroMethoxy)-benzoic acid;Benzoic acid, 4-bromo-2-chloro-5-(trifluoromethoxy)-
• CAS NO: 1419075-84-5
• Molecular Formula: C₈H₃BrClF₃O₃
• Molecular Weight: 319.46
• Mol File: 1419075-84-5.mol

Chemical Properties

• Boiling Point: 307.7±42.0 °C(Predicted)
• Appearance: /
• Density: 1.873±0.06 g/cm3(Predicted)
• PKA: 2.24±0.25(Predicted)
• CAS DataBase Reference: 2-Chloro-4-broMo-5-(trifluoroMethoxy)-benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-4-broMo-5-(trifluoroMethoxy)-benzoic acid(1419075-84-5)
• EPA Substance Registry System: 2-Chloro-4-broMo-5-(trifluoroMethoxy)-benzoic acid(1419075-84-5)

Safety Data

• Hazardous Substances Data: 1419075-84-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-bromo-2-chloro-5-trifluoromethoxy-benzoic acid is used as an intermediate in the synthesis of pharmaceuticals for its unique structural features. The presence of bromine and chlorine atoms allows for further functionalization and the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical sector, 4-bromo-2-chloro-5-trifluoromethoxy-benzoic acid is utilized as a precursor in the production of agrochemicals. Its chemical structure contributes to the development of compounds with pesticidal or herbicidal activities, enhancing crop protection and yield.
Used in Dye Industry:
4-bromo-2-chloro-5-trifluoromethoxy-benzoic acid is employed as a building block in the synthesis of dyes. The presence of the trifluoromethoxy group and halogens imparts color and stability to the resulting dyes, making them suitable for various applications in textiles, inks, and other industries.
Used in Medicinal Chemistry Research:
4-bromo-2-chloro-5-trifluoromethoxy-benzoic acid serves as a valuable starting material in medicinal chemistry research. Its unique structure allows for the exploration of new chemical space and the development of potential drug candidates with novel mechanisms of action.
Used in Organic Synthesis:
4-bromo-2-chloro-5-trifluoromethoxy-benzoic acid is used as a versatile building block in organic synthesis. Its functional groups enable the creation of complex organic molecules for various applications, including the development of new materials, catalysts, and specialty chemicals.

Upstream product

• 1433280-56-8 4-bromo-2-chloro-5-trifluoromethoxy-benzoic acid methyl ester 
• 1433280-57-9 (4-bromo-2-chloro-5-trifluoromethoxy-phenyl)-methanol 
• 1261483-31-1 (2-chloro-5-trifluoromethoxy-phenyl)-methanol 
• 1261649-12-0 2-chloro-5-trifluoromethoxy-benzoic acid methyl ester 
• 468075-00-5 1-bromo-2-chloro-4-(trifluoromethoxy)benzene 

Downstream Products

• 1433280-58-0 (R)-4-[5-(4-bromo-2-chloro-5-trifluoromethoxy-benzoylamino)-pyridin-2-yl]-3-methyl-piperazine-1-carboxylic acid tert-butyl ester 

Relevant articles and documents

HEPATITIS C VIRUS INHIBITORS

The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.