AN EFFICIENT SYNTHESIS OF OPTICALLY ACTIVE 4-BENZYLOXY-3-HYDROXY-1-BUTYNE AND ITS CROSS-COUPLING REACTION
An efficient procedure for the synthesis of optically active 4-benzyloxy-3-hydroxy-1-butyne (12: R=H) has been established starting with optically active tartrate ester.Cross-coupling reaction of the resulted acetylene (12: R=H) with some aromatic halides