- Synthesis of highly functionalized polycyclic quinoxaline derivatives using visible-light photoredox catalysis
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A mild and facile method for preparing highly functionalized pyrrolo[1,2-a]quinoxalines and other nitrogenrich heterocycles, each containing a quinoxaline core or an analogue thereof, has been developed. The novel method features a visible-light-induced decarboxylative radical coupling of ortho-substituted arylisocyanides and radicals generated from phenyliodine(III) dicarboxylate reagents and exhibits excellent functional group compatibility. A wide range of quinoxaline heterocycles have been prepared. Finally, a telescoped preparation of these polycyclic compounds by integration of the in-line isocyanide formation and photochemical cyclization has been established in a three-step continuousflow system.
- He, Zhi,Bae, Minwoo,Wu, Jie,Jamison, Timothy F.
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p. 14451 - 14455
(2015/02/19)
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- Application of the Pictet-Spengler reaction to aryl amine substrates linked to deactivated aromatic heterosystems
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Three new substrates with an aryl amine moiety attached to quinoxalines, triazoles and tetrazoles either via C or N have been used for the Pictet-Spengler reaction. The substrates have been designed by applying the concept of 'aryl amine attached to a dea
- Saha,Sharma,Sawant,Kundu
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p. 8676 - 8684
(2008/12/21)
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- SYNTHESIS AND PROPERTIES OF PHENYLENEBIS-1H-TETRAZOLES
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Heterocyclization of m- and p-phenylenediamines with orthoformic ester and sodium azide has given phenylenebis-1H-tetrazoles.Under these conditions, o-phenylenediamine gives benzimidazole. o-, m-, and p-Phenylenebis-1H-tetrazoles were also obtained from the nitroanilines via the intermediate nitro- and aminophenyltetrazoles.The reactions of the bistetrazoles examined were basic hydrolysis, aminomethylation, and complex formation with copper salts.
- Gaponik, P. N.,Karavai, V. P.,Davshko, I. E.,Degtyarik, M. M.,Bogatikov, A. N.
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p. 1274 - 1278
(2007/10/02)
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