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1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline is a white solid compound that is identified as an impurity in Fosinopril (F727800), a phosphinic acid containing ACE inhibitor known for its antihypertensive properties.

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  • 1421283-57-9 Structure
  • Basic information

    1. Product Name: 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline
    2. Synonyms: 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline;FNDUAIAJNMDGCJ-NEPJUHHUSA-N
    3. CAS NO:1421283-57-9
    4. Molecular Formula: C14H23NO3
    5. Molecular Weight: 253.33732
    6. EINECS: N/A
    7. Product Categories: Aromatics, Chiral Reagents, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Phosphorylating and Phosphitylating Agents
    8. Mol File: 1421283-57-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 443.2±38.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.152±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: Refrigerator
    8. Solubility: Chloroform (Slightly), Methanol (Slightly)
    9. PKA: 3.70±0.40(Predicted)
    10. CAS DataBase Reference: 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline(1421283-57-9)
    12. EPA Substance Registry System: 1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline(1421283-57-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1421283-57-9(Hazardous Substances Data)

1421283-57-9 Usage

Uses

Used in Pharmaceutical Industry:
1-(1-Oxopropyl)-(4S)-4-cyclohexyl-L-proline is used as an impurity in the production of Fosinopril, an ACE inhibitor, for its role in managing high blood pressure. As an impurity, it is essential to monitor and control its presence to ensure the safety and efficacy of the antihypertensive medication.
Additionally, given its chemical structure, it may have potential applications in other areas of the pharmaceutical industry, such as the development of new drugs or as an intermediate in the synthesis of other bioactive compounds. However, further research and development would be required to explore these possibilities.

Check Digit Verification of cas no

The CAS Registry Mumber 1421283-57-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,1,2,8 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1421283-57:
(9*1)+(8*4)+(7*2)+(6*1)+(5*2)+(4*8)+(3*3)+(2*5)+(1*7)=129
129 % 10 = 9
So 1421283-57-9 is a valid CAS Registry Number.

1421283-57-9Upstream product

1421283-57-9Downstream Products

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