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AR-13324 (mesylate) is a chemical compound that functions as a selective Rho kinase (ROCK) inhibitor, exhibiting potential in the treatment of various ocular conditions. It is recognized for its ability to reduce intraocular pressure and enhance ocular blood flow, making it a promising candidate for managing glaucoma and dry eye syndrome.

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  • 1422144-42-0 Structure
  • Basic information

    1. Product Name: AR-13324 (mesylate)
    2. Synonyms: AR-13324 (mesylate);Netarsudil Mesylate;Benzoic acid, 2,4-dimethyl-, [4-[(1S)-1-(aminomethyl)-2-(6-isoquinolinylamino)-2-oxoethyl]phenyl]methyl ester, methanesulfonate (1:2)
    3. CAS NO:1422144-42-0
    4. Molecular Formula: C30H35N3O9S2
    5. Molecular Weight: 645.7436
    6. EINECS: N/A
    7. Product Categories: API
    8. Mol File: 1422144-42-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: AR-13324 (mesylate)(CAS DataBase Reference)
    10. NIST Chemistry Reference: AR-13324 (mesylate)(1422144-42-0)
    11. EPA Substance Registry System: AR-13324 (mesylate)(1422144-42-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1422144-42-0(Hazardous Substances Data)

1422144-42-0 Usage

Uses

Used in Ophthalmology:
AR-13324 (mesylate) is used as a therapeutic agent for the treatment of glaucoma, a condition that can result in vision loss if untreated. It is utilized for its capacity to lower intraocular pressure, a key factor in the progression of the disease.
Used in Dry Eye Syndrome Treatment:
In the management of dry eye syndrome, AR-13324 (mesylate) is employed to stimulate tear production and reduce inflammation within the eye. This dual action addresses both the symptoms and underlying causes of the condition, offering a comprehensive approach to treatment.
Clinical trials and studies have underscored the safety and efficacy of AR-13324 (mesylate), supporting its ongoing development as a valuable treatment option for these ocular health concerns.

Check Digit Verification of cas no

The CAS Registry Mumber 1422144-42-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,2,1,4 and 4 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1422144-42:
(9*1)+(8*4)+(7*2)+(6*2)+(5*1)+(4*4)+(3*4)+(2*4)+(1*2)=110
110 % 10 = 0
So 1422144-42-0 is a valid CAS Registry Number.

1422144-42-0Upstream product

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