- Synthesis and anthelmintic activity of 7-hydroxy-5-oxo-5H-thieno[3,2- b]pyran-6-carboxanilides and -6-thiocarboxanilides
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7-Hydroxy-5-oxo-5H-thieno[3,2-b]pyran-6-carboxanilides and -6- thiocarboxanilides represent a novel series of anthelmintic compounds, with broad-spectrum activity against important parasitic nematodes in sheep and dogs. In particular, an improved efficacy against Trichostrongylus colubriformis in sheep over the related 3-carbamoyl-4-hydroxycoumarins has been noted. New synthetic routes to the key intermediate, 7- hydroxythieno[3,2-b]pyran-5-one, have been developed.
- Plant,Harder,Mencke,Bertram
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p. 351 - 358
(2007/10/03)
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- Substituted thieno[3,2-b]pyran-5,7-diones
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Novel substituted thieno[3,2-b]pyran-5,7-diones of the general formula (I) STR1 Processes for their preparation and their use as herbicides and as plant growth regulators and novel intermediates of the formula (VI) STR2 (in which R1, R2, X, Y and Z have the meaning given in the description).
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