Asymmetrie synthesis of y-chloro-α,β-diaminoand β,y-aziridino-α-aminoacylpyrrolidinesand -piperidines via stereoselective Mannich-type additions of N-(diphenylmethylene)glycinamides across α-chloro-N-sulfinylimines
The asymmetric synthesis of new chiral γ-chloro-α,β- diaminocarboxylamide derivatives by highly diastereoselective Mannich-type reactions of N-(diphenylmethylene)glycinamides across chiral α-chloro-N-p-toluenesulfinylaldimines was developed. The resulting