- Solvent-regulated coupling of 2-alkynylbenzaldehydes with cyclic amines: Selective synthesis of fused N-heterocycles and functionalized naphthalene derivatives
-
An efficient synthesis of 1,2,3,4-tetrahydrobenzo[g]-quinoline derivatives through PdCl2-catalyzed, TBHP-promoted, and toluene-mediated dehydrogenation/[4+2] cycloaddition of saturated cyclic amines with 2-alkynylbenzaldehydes was developed. On the contrary, when the reaction medium was changed from toluene to DMSO/H2O, another class of important compounds, naphthyl chain amines, formed via a dehydrogenation?intermolecular condensation? C?N bond cleavage?intramolecular condensation pathway, was obtained with good selectivity.
- He, Yan,Fan, Xuesen,Zheng, Zhi,Liu, Qimeng,Zhang, Xinying
-
supporting information
p. 9053 - 9058
(2020/12/02)
-
- Synthesis of 1-aminoisoquinolines by gold(III)-mediated domino reactions from 2-alkynylbenzamides and ammonium acetate
-
A facile synthetic route toward pharmaceutically interesting 1-aminoisoquinoline derivatives by gold(III)-mediated domino reactions is described. This synthetic protocol starts from readily available 2-alkynylbenzamides and ammonium acetate and takes plac
- Long, Yuhua,She, Zhigang,Liu, Xiaochen,Chen, Yu
-
p. 2579 - 2588
(2013/04/24)
-