Efficient synthesis of arylaldehyde oxime ethers functionalised with 3,4-dihydropyrimidinones and 2,5-quinazolinediones via a one-pot two-step method
New arylahdehyde oxime ethers functionalised with N3-3,4- dihydropyrimidinone and 2,5-quinazolinedione groups were synthesised in moderate to good yields by the reaction of the corresponding 3,4-dihydropyrimidinones and quinazolinediones with paraformaldehyde and arylaldehyde oximes via a one-pot two-step strategy in the presence of chlorotrimethylsilane. The advantages of this method are the simple procedure, the high regioselectivity of the products and the mild reaction conditions.