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1428857-72-0

C17H14N2O3 is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1428857-72-0 Structure

  • Basic information

    1. Product Name: C17H14N2O3
    2. Synonyms:
    3. CAS NO:1428857-72-0
    4. Molecular Formula:
    5. Molecular Weight: 294.31
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1428857-72-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: C17H14N2O3(CAS DataBase Reference)
    10. NIST Chemistry Reference: C17H14N2O3(1428857-72-0)
    11. EPA Substance Registry System: C17H14N2O3(1428857-72-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1428857-72-0(Hazardous Substances Data)

1428857-72-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1428857-72-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,2,8,8,5 and 7 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1428857-72:
(9*1)+(8*4)+(7*2)+(6*8)+(5*8)+(4*5)+(3*7)+(2*7)+(1*2)=200
200 % 10 = 0
So 1428857-72-0 is a valid CAS Registry Number.

1428857-72-0Downstream Products

1428857-72-0Relevant articles and documents

Exploring the UDP pocket of LpxC through amino acid analogs

Hale, Michael R.,Hill, Pamela,Lahiri, Sushmita,Miller, Matthew D.,Ross, Philip,Alm, Richard,Gao, Ning,Kutschke, Amy,Johnstone, Michele,Prince, Bryan,Thresher, Jason,Yang, Wei

, p. 2362 - 2367 (2013/05/09)

Lipopolysaccharide (LPS) biosynthesis is an attractive antibacterial target as it is both conserved and essential for the survival of key pathogenic bacteria. Lipid A is the hydrophobic anchor for LPS and a key structural component of the outer membrane of Gram-negative bacteria. Lipid A biosynthesis is performed in part by a unique zinc dependent metalloamidase, LpxC (UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase), which catalyzes the first non-reversible step in lipid A biosynthesis. The UDP portion of the LpxC substrate-binding pocket has been relatively unexplored. We have designed and evaluated a series of hydroxamate based inhibitors which explore the SAR of substitutions directed into the UDP pocket with a range of substituted α-amino acid based linkers. We also provide the first wild type structure of Pseudomonas aeruginosa LpxC which was utilized in the design of many of these analogs.

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