De novo fragment design: A medicinal chemistry approach to fragment-based lead generation
The use of fragments with low binding affinity for their targets as starting points has received much attention recently. Screening of fragment libraries has been the most common method to find attractive starting points. Herein, we describe a unique, alt
Talamas, Francisco X.,Ao-Ieong, Gloria,Brameld, Ken A.,Chin, Elbert,De Vicente, Javier,Dunn, James P.,Ghate, Manjiri,Giannetti, Anthony M.,Harris, Seth F.,Labadie, Sharada S.,Leveque, Vincent,Li, Jim,Lui, Alfred S-T.,McCaleb, Kristen L.,Nájera, Isabel,Schoenfeld, Ryan C.,Wang, Beihan,Wong, April
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p. 3115 - 3119
(2013/05/21)
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