- Synthesis and pharmacologic examination of derivatives of benzoxazaphosphoryl-4-one and 2-phenyl-10-methyl-3a-triethoxyphosphone-1H,2,3,9,10-tetrahydropyrrolo [3,4-b][1,4]benzoxazepine-1,3,9-trione
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A series of N-derivatives of 2-phenyl-2,3-dihydro-1,3,2(lambda 5)- benzoxazaphosphoryl-4-one and 2-phenyl-10-methyl-3a-triethoxyphosphonio- 1H,2,3,9,10-tetrahydropyrrolo[3,4-b]([1,4]benzoxazepine-1,3,9-trio ne have been prepared. The pharmacological investigation of the above mentioned compounds shows antitumor action against leukaemia in the case of three N-derivatives.
- Porada,Budzisz,Graczyk,Pakulska
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p. 173 - 178
(2007/10/02)
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- Synthesis and anticancer activity of 2-phenyl-3-alkyl(aryl)-2,3-dihydro-1,3,2(λ5)-benzoxazaphosphorin-4-o ne derivatives
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Preparation of 2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one derivatives and their 2-oxo derivatives is described. Compounds 1 and 12 have anticancer activity.
- Kostka,Porada
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p. 325 - 328
(2007/10/02)
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