143000-22-0

Basic information

• Product Name: 3-(methylamino)-2-phenyl-2,3-dihydro-4H-1,3,2-benzoxazaphosphinin-4-one 2-oxide
• CAS NO: 143000-22-0
• Molecular Formula: C₁₄H₁₃N₂O₃P
• Molecular Weight: 288.2384
• Mol File: 143000-22-0.mol

Chemical Properties

• Boiling Point: 432.1°C at 760 mmHg
• Flash Point: 215.1°C
• Density: 1.39g/cm³
• Vapor Pressure: 1.14E-07mmHg at 25°C
• Refractive Index: 1.641
• CAS DataBase Reference: 3-(methylamino)-2-phenyl-2,3-dihydro-4H-1,3,2-benzoxazaphosphinin-4-one 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(methylamino)-2-phenyl-2,3-dihydro-4H-1,3,2-benzoxazaphosphinin-4-one 2-oxide(143000-22-0)
• EPA Substance Registry System: 3-(methylamino)-2-phenyl-2,3-dihydro-4H-1,3,2-benzoxazaphosphinin-4-one 2-oxide(143000-22-0)

Safety Data

• Hazardous Substances Data: 143000-22-0(Hazardous Substances Data)

Upstream product

• 824-72-6 P,P-dichlorophenylphosphine oxide 
• 3583-73-1 Salicylsaeure-N'-methylhydrazid 

Relevant articles and documents

Synthesis and pharmacologic examination of derivatives of benzoxazaphosphoryl-4-one and 2-phenyl-10-methyl-3a-triethoxyphosphone-1H,2,3,9,10-tetrahydropyrrolo [3,4-b][1,4]benzoxazepine-1,3,9-trione

A series of N-derivatives of 2-phenyl-2,3-dihydro-1,3,2(lambda 5)- benzoxazaphosphoryl-4-one and 2-phenyl-10-methyl-3a-triethoxyphosphonio- 1H,2,3,9,10-tetrahydropyrrolo[3,4-b]([1,4]benzoxazepine-1,3,9-trio ne have been prepared. The pharmacological investigation of the above mentioned compounds shows antitumor action against leukaemia in the case of three N-derivatives.

Synthesis and anticancer activity of 2-phenyl-3-alkyl(aryl)-2,3-dihydro-1,3,2(λ5)-benzoxazaphosphorin-4-o ne derivatives

Preparation of 2,3-dihydro-1,3,2-benzoxazaphosphorin-4-one derivatives and their 2-oxo derivatives is described. Compounds 1 and 12 have anticancer activity.