143655-56-5 Usage
Uses
Used in Pharmaceutical Industry:
7-fluoro-8-Methyl-5-nitro-1,2,3,4-tetrahydronaphthalen-1-one is used as an antiarrhythmic medication for the treatment and prevention of certain types of irregular heartbeats. It functions by blocking specific electrical signals in the heart, which helps regulate heart rhythm and mitigates the risk of life-threatening heart conditions. Due to its potential side effects and interactions with other medications, amiodarone should be administered under the guidance of a healthcare professional to ensure safe and effective treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 143655-56-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,3,6,5 and 5 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 143655-56:
(8*1)+(7*4)+(6*3)+(5*6)+(4*5)+(3*5)+(2*5)+(1*6)=135
135 % 10 = 5
So 143655-56-5 is a valid CAS Registry Number.
143655-56-5Relevant articles and documents
Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues
Sugimori, Masamichi,Ejima, Akio,Ohsuki, Satoru,Uoto, Kouichi,Mitsui, Ikuo,Kawato, Yasuyoshi,Hirota, Yasuhide,Sato, Keiki,Terasawa, Hirofumi
, p. 2308 - 2318 (2007/10/03)
Nineteen ring A- and F-modified hexacyclic analogues of camptothecin were synthesized by Friedlander condensation of appropriately substituted bicyclic amino ketones with tricyclic ketone and were evaluated for cytotoxicity and topoisomerase I inhibitory
Hexa-cyclic compound
-
, (2008/06/13)
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: STR1 The compound is prepared from an aminoketone compound and a pyranoindolizine compound by the condensation-ring closing reaction. It is abundantly water-soluble, and has an excellent antitumour activity and a high degree of safety, and can be applied as an antitumour medicine for curing tumors of various kinds.
