Hydrazone as the directing group for Ir-catalyzed arene diborylations and sequential functionalizations
The use of hemilabile pyridine-hydrazone N,N-ligands allows the highly selective Ir-catalyzed ortho,ortho'-directed diborylation of aromatic N,N-dimethylhydrazones in near-quantitative yields. One-pot sequential Suzuki-Miyaura cross-coupling with different aryl bromides provides a short entry to unsymmetrically substituted 2,6-diarylbenzaldehyde derivatives.
Ros, Abel,Lopez-Rodriguez, Rocio,Estepa, Beatriz,Alvarez, Eleuterio,Fernandez, Rosario,Lassaletta, Jose M.
supporting information; experimental part
p. 4573 - 4576
(2012/04/23)
Improved efficient conversion of aldehydes to nitriles via their N,N- dimethyl hydrazones
Aldehyde N,N-dimethylhydrazones undergoes facile oxidative cleavage to nitriles on reaction with DMS and K2CO3 in quantitative yields. Nitriles can also be easily obtained in high yields in a 'one-pot' process starting from the corresponding aldehydes.
Kamal, Ahmed,Arifuddin,Venugopal Rao
p. 4507 - 4512
(2007/10/03)
More Articles about upstream products of 14371-17-6