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CAS

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1437316-91-0

2,4-difluoro-3-iodoaniline is an organic compound characterized by the presence of two fluorine atoms at the 2nd and 4th positions, and an iodine atom at the 3rd position on the aniline molecule. It is a synthetic intermediate with potential applications in the pharmaceutical and chemical industries due to its unique structural features.

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  • 1437316-91-0 Structure

  • Basic information

    1. Product Name: 2,4-difluoro-3-iodoaniline
    2. Synonyms: 2,4-difluoro-3-iodoaniline
    3. CAS NO:1437316-91-0
    4. Molecular Formula:
    5. Molecular Weight: 255.006
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1437316-91-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 266.7±40.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 2.086±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,4-difluoro-3-iodoaniline(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,4-difluoro-3-iodoaniline(1437316-91-0)
    11. EPA Substance Registry System: 2,4-difluoro-3-iodoaniline(1437316-91-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1437316-91-0(Hazardous Substances Data)

1437316-91-0 Usage

Uses

Used in Pharmaceutical Industry:
2,4-difluoro-3-iodoaniline is used as a synthetic intermediate for the preparation of purine derivatives. These derivatives act as protein kinase modulators, which are crucial in the treatment and prevention of protein kinase-mediated diseases. By targeting specific protein kinases, these modulators can help regulate cellular processes and potentially lead to therapeutic benefits for various conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1437316-91-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,3,7,3,1 and 6 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1437316-91:
(9*1)+(8*4)+(7*3)+(6*7)+(5*3)+(4*1)+(3*6)+(2*9)+(1*1)=160
160 % 10 = 0
So 1437316-91-0 is a valid CAS Registry Number.

1437316-91-0Relevant articles and documents

HETEROCYCLIC COMPOUND

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Paragraph 0870; 0871, (2019/06/17)

Provided is a heterocyclic compound that may have a GCN2 inhibitory action, and is expected to be useful for the prophylaxis or treatment of GCN2 associated diseases including cancer and the like. A compound represented by the formula (I): wherein each symbol is as described in the DESCRIPTION, or a salt thereof.

Protein kinase inhibitor and its composition and use thereof

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Paragraph 0501-0503, (2017/08/02)

The invention relates to compounds as shown in the general formula (I), pharmaceutical compositions containing the compounds, a method for treating diseases and disease symptoms related to abnormal activity of protein kinase by using the compounds, and medicinal use of the compounds.

KINASE MODULATING COMPOUNDS, COMPOSITIONS CONTAINING THE SAME AND USE THEREOF

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Page/Page column 57, (2013/06/05)

The invention provides a compound represented by formula (I) which may modulate a kinase, and a pharmaceutical composition thereof, as well as the method for preventing or treating a protein kinase mediated disease or condition.

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