Regioselective di- and tetra-functionalisation of γ-cyclodextrin using capping methodology
Alkylation of γ-cyclodextrin with 3 equiv. of 1,3-bis[bis(4-tert- butylphenyl)chloromethyl]benzene, followed by permethylation afforded selectively a singly capped (A,B), as well as two doubly capped (A,B:D,E and A,B:E,F) methylated γ-CDs. Deprotection with HBF4 gave quantitatively the corresponding diols and tetrols, which constitute valuable starting compounds for further functionalisation. The Royal Society of Chemistry 2013.
Get Best Price for1438264-45-96A,6B:6E,6F-tetra-O-bis{benzene-1,3-bis[bis(4-tert-butylphenyl)methyl]}-2A,2B,2C,2D,2E,2F,2G,2H,3A,3B,3C,3D,3E,3F,3G,3H,6C,6D,6G,6H-icosa-O-methyl-γ-cyclodextrin