- TRICHLOROETHYLENE IN ORGANIC SYNTHESIS: II. REACTION OF TRICHLOROETHYLENE WITH SECONDARY AMINES
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In a novel reaction, trichloroethylene reacts with secondary aliphatic amines in the presence of aqueous solution of NaOH and catalytic quantity of benzyltriethylammonium chloride to give the corresponding N,N,N',N'-tetraalkylsubstituted glycinamides.The following glycinamides were obtained with high yield: (N-morpholine)acetic acid morpholide, N-(piperidineacetyl)piperidine, N,N,N',N'-tetra-n-butylglycinamide and N,N,N',N'-tetraethylglycinamide.Mechanism of the reaction is discussed.
- Pielichowski, Jan,Popielarz, Roman
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p. 2671 - 2676
(2007/10/02)
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