Synthesis and Pharmacological Characteization of 2-(4-Chloro-3-hydroxyphenyl)ethylamine and N,N-Dialkyl Derivatives as Dopamine Receptor Ligands
2-(4-chloro-3-hydroxyphenyl)ethylamine (4) and some derivatives were synthesized as dopamine (DA) receptor ligands.Amine 4 retains the dopaminergic pharmacophore 2-(3-hydroxyphenyl)ethylamine, and the chlorine atom replaces the "para" hydroxyl group of DA
Claudi, Francesco,Giorgioni, Gianfabio,Stefano, Antonio Di,Abbracchio, Maria Pia,Paoletti, Anna Maria,et al.
p. 4408 - 4414
(2007/10/02)
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