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144332-60-5

N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 144332-60-5 Structure

  • Basic information

    1. Product Name: N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE
    2. Synonyms: Z-N-METHYL-ALPHA-AMINOISOBUTYRIC ACID;Z-N-METHYL-ALPHA-METHYLALANINE;Z-N-ME-AIB-OH;Z-N,2-DIMETHYLALANINE;N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE;N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE, 98 %;N-[(benzyloxy)carbonyl]-N,2-diMethylalanine;Z-N-methyl-α-aminoisobutyric acid
    3. CAS NO:144332-60-5
    4. Molecular Formula: C13H17NO4
    5. Molecular Weight: 251.28
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 144332-60-5.mol

  • Chemical Properties

    1. Melting Point: 135-138 °C(lit.)
    2. Boiling Point: 394.8°Cat760mmHg
    3. Flash Point: 192.6°C
    4. Appearance: /
    5. Density: 1.195g/cm3
    6. Vapor Pressure: 6.1E-07mmHg at 25°C
    7. Refractive Index: 1.54
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. PKA: 4.16±0.10(Predicted)
    11. BRN: 3347632
    12. CAS DataBase Reference: N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE(CAS DataBase Reference)
    13. NIST Chemistry Reference: N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE(144332-60-5)
    14. EPA Substance Registry System: N-CARBOBENZYLOXY-N,2-DIMETHYLALANINE(144332-60-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 144332-60-5(Hazardous Substances Data)

144332-60-5 Usage

Chemical Properties

White to off-white powder

Check Digit Verification of cas no

The CAS Registry Mumber 144332-60-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,4,3,3 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 144332-60:
(8*1)+(7*4)+(6*4)+(5*3)+(4*3)+(3*2)+(2*6)+(1*0)=105
105 % 10 = 5
So 144332-60-5 is a valid CAS Registry Number.
InChI:InChI=1/C13H17NO4/c1-13(2,11(15)16)14(3)12(17)18-9-10-7-5-4-6-8-10/h4-8H,9H2,1-3H3,(H,15,16)

144332-60-5 Well-known Company Product Price

  • Brand
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  • Detail

  • Aldrich

  • (192902)  Z-N-Me-Aib-OH  98%

  • 144332-60-5

  • 192902-1G

  • 253.89CNY

  • Detail

144332-60-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methyl-2-[methyl(phenylmethoxycarbonyl)amino]propanoic acid

1.2 Other means of identification

Product number -
Other names N-Cbz-N,2-dimethylalanine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:144332-60-5 SDS

144332-60-5Downstream Products

144332-60-5Relevant articles and documents

Trimethyl-substituted carbamate as a versatile self-immolative linker for fluorescence detection of enzyme reactions

Inoue, Kazuya,Nakamura, Noriaki,Ojida, Akio,Uchinomiya, Shohei

supporting information, (2020/05/25)

Self-immolative linker is a useful building block of molecular probes, with broad applications in the fields of enzyme activity analysis, stimuli-responsive material science, and drug delivery. This manuscript presents N-methyl dimethyl methyl (i.e., trimethyl) carbamate as a new class of self-immolative linker for the fluorescence detection of enzyme reactions. The trimethyl carbamate was shown to spontaneously undergo intramolecular cyclization upon formation of a carboxylate group, to liberate a fluorophore with the second time rapid reaction kinetics. Interestingly, the auto-cleavage reaction of trimethyl carbamate was also induced by the formation of hydroxyl and amino groups. Fluorescent probes with a trimethyl carbamate could be applicable for fluorescence monitoring of the enzyme reactions catalyzed by esterase, ketoreductase, and aminotransferase, and for fluorescence imaging of intracellular esterase activity in living cells, hence demonstrating the utility of this new class of self-immolative linker.

N-METHYL AMINO ACIDS

-

Page 86-87, (2010/02/06)

The present invention relates to a compound of formula (I) or (II), processes for preparing them, peptides including them and kits involving them.

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