144404-96-6

Basic information

• Product Name: 1,3-Dioxane-2-carboxaldehyde, 2,4-dimethyl-, (2R-trans)- (9CI)
• Synonyms: 1,3-Dioxane-2-carboxaldehyde, 2,4-dimethyl-, (2R-trans)- (9CI)
• CAS NO: 144404-96-6
• Molecular Formula: C7H12O3
• Molecular Weight: 144.16838
• Product Categories: ALDEHYDE
• Mol File: 144404-96-6.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxane-2-carboxaldehyde, 2,4-dimethyl-, (2R-trans)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-2-carboxaldehyde, 2,4-dimethyl-, (2R-trans)- (9CI)(144404-96-6)
• EPA Substance Registry System: 1,3-Dioxane-2-carboxaldehyde, 2,4-dimethyl-, (2R-trans)- (9CI)(144404-96-6)

Safety Data

• Hazardous Substances Data: 144404-96-6(Hazardous Substances Data)

Usage

Synthesis of pharmaceuticals and fragrances

Piperonal is used as a key intermediate in the synthesis of various pharmaceuticals and fragrances.

Flavoring agent

It is also used as a flavoring agent in the food industry.

Production of dyes

Piperonal is used in the production of certain dyes.

Upstream product

• 132830-72-9 (2R,4R)-2-hydroxymethyl-2,4-dimethyl-1,3-dioxane 
• 132830-73-0 (2S,4R)-2-hydroxymethyl-2,4-dimethyl-1,3-dioxane 
• 132735-32-1 (2S,4R)-2-methoxycarbonyl-2,4-dimethyl-1,3-dioxane 
• 132735-31-0 (2R,4R)-2-methoxycarbonyl-2,4-dimethyl-1,3-dioxane 

Relevant articles and documents

Distinction of Diastereofaces at the α-Position of Chiral Cyclic Acetals

Key words: chiral acetal; asymmetric 1,2-addition; asymmetric 1,4-addition; C2 symmetry; determination of optical purity; chiral carboxylic acid Asymmetric 1,2- and 1,4-additions to substrates with an acetal as a chiral auxiliary have been studied.Among the tested substrates, C2-symmetrical 5c was most effective for 1,2-addition with MeTi(O-iPr)3.Furthermore, C2-symmetrical carbinol 5b has been found to be a potent 1H-NMR reagent for determination of optical purity of carboxylic acids with a chiral center at the α-position.