144583-88-0

Basic information

• Product Name: 6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one
• Synonyms: 6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one;6-Amino-1,4,4-trimethyl-3,4-dihydro-1H-quinolin-2-one;6-Amino-1,4,4-trimethyl-3,4-dihydroquinolin-2(1H)-one
• CAS NO: 144583-88-0
• Molecular Formula: C₁₂H₁₆N₂O
• Molecular Weight: 204.26824
• Mol File: 144583-88-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one(144583-88-0)
• EPA Substance Registry System: 6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one(144583-88-0)

Safety Data

• Hazardous Substances Data: 144583-88-0(Hazardous Substances Data)

Usage

Uses

Used in Drug Development:
6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one is used as a potential candidate in drug development due to its pharmacological properties. It has been studied for its potential use in treating various diseases and conditions.
Used in Organic Synthesis:
6-amino-3,4-dihydro-1,4,4-trimethylquinolin-2(1H)-one is used as a building block in organic synthesis for the preparation of various compounds. Its unique chemical structure allows it to be a valuable component in the synthesis of new and useful molecules.

Upstream product

• 144583-89-1 1,4,4-trimethyl-6-nitro-3,4-dihydroquinolin-2(1H)-one 

Downstream Products

• 144583-53-9 ethyl p-[(1,2,3,4-tetrahydro-1,4,4-trimethyl-2-oxo-6-quinolinyl)carbamoyl]-benzoate 

Relevant articles and documents

Synthesis of potential Rho-kinase inhibitors based on the chemistry of an original heterocycle: 4,4-Dimethyl-3,4-dihydro-1H-quinolin-2-one

A new series of substituted 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one have been prepared via condensation of 3,3-dimethylacryloyl chloride with aniline. Details of synthetic procedures are shown. Our aim was to investigate the potency of our original het

Carboxamides and anilides

Described herein are compounds of the formula STR1 wherein R1 signifies hydrogen, lower-alkyl or a cation; R2 signifies hydrogen, lower-alkyl, lower-alkoxy or halogen; M signifies --CONH-- or --NHCO--; X and Y are each independently selected from the group consisting of >CR3 R4 and --CONR5 --; Z signifies >CR6 R7 ; R3, R4, R6 and R7 are each independently selected from the group consisting of hydrogen and lower-alkyl; R5 signifies alkyl; and n signifies 0, 1 or 2; provided that at least one of X or Y is --CONR5 -- which is bonded to the phenyl ring via the N atom. These compounds are useful in the treatment and prophylaxis of neoplasms, dermatoses and aging of the skin.