144775-26-8

Upstream product

• 144831-05-0 (S)-4-[(2S,3R)-3-Benzyloxy-1-(4-methoxy-phenyl)-4-oxo-azetidin-2-yl]-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 127940-39-0 (S)-4-{[(E)-4-Methoxy-phenylimino]-methyl}-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 141268-44-2 1-(4-methoxyphenyl)-3-(phenylmethoxy)-4-(1,4-dioxaspiro<4.5>dec-2-yl)azetidin-2-one 
• 139007-45-7 S-(2-Pyridyl) 2-(phenylmethoxy)ethanethioate 
• 149818-33-7 (+)-(3R,4S)-cis-3-benzyloxy-4-[(S)-1',2'-dihydroxyethyl]-1-(p-methoxyphenyl)-2-azetidinone 
• 104-94-9 4-methoxy-aniline 
• 19810-31-2 Benzyloxyacetyl chloride 
• 144831-06-1 (3R,4S)-4-((S)-1-Amino-2-hydroxy-ethyl)-3-benzyloxy-1-(4-methoxy-phenyl)-azetidin-2-one 
• 148968-08-5 (+)-(3R,4R)-1-(p-anisyl)-3-benzyloxy-4-formyl-2-azetidinone 
• 141781-23-9 [(S)-1-(1,4-Dioxa-spiro[4.5]dec-2-yl)-meth-(E)-ylidene]-(4-methoxy-phenyl)-amine 
• 148903-76-8 (3R,4S,4'S,5'S) N-(p-anisyl)-3-benzyloxy-4-azetidin-2-one 
• 148903-81-5 (3R,4S)-4-((1S,2S)-1-Amino-2-hydroxy-2-phenyl-ethyl)-3-benzyloxy-1-(4-methoxy-phenyl)-azetidin-2-one 

Downstream Products

• 144775-28-0 (2R,3R)-3-Benzyloxy-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid tert-butyl ester 
• 144775-42-8 (2R,3R)-3-Benzyloxy-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid (1R,2S,5R)-2-isopropyl-5-methyl-cyclohexyl ester 
• 144775-27-9 (2R,3R)-3-Benzyloxy-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 946436-04-0 3-Benzyloxy-1-(4-methoxy-phenyl)-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 144831-07-2 (2R,3R)-3-Benzyloxy-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 144775-33-7 (2R,3R)-2-Benzoylamino-3-benzyloxy-succinic acid 1-tert-butyl ester 4-ethyl ester 
• 144775-34-8 (2R,3R)-2-Benzyloxy-3-tert-butoxycarbonylamino-succinic acid 4-tert-butyl ester 1-methyl ester 
• 144775-32-6 (2R,3R)-2-Benzoylamino-3-benzyloxy-succinic acid diethyl ester 
• 144775-31-5 (2R,3R)-2-Amino-3-benzyloxy-succinic acid 1-tert-butyl ester 4-ethyl ester 
• 144775-30-4 Diethyl (β-benzyloxy)aspartate 
• 144775-29-1 (2R,3R)-3-Benzyloxy-4-oxo-azetidine-2-carboxylic acid tert-butyl ester 
• 104211-17-8 (2S,3R)-3-Benzyloxy-4-oxo-azetidine-2-carboxylic acid ethyl ester 
• 184424-00-8 (R)-3-Benzyloxy-1-(4-methoxy-phenyl)-azetidin-2-one 

Relevant academic research and scientific papers

A new radical route to C4-unsubstituted β-lactams

C4-Unsubstituted β-lactams 3 are conveniently prepared from easily available 4-formyl-β-lactams 1, in a sequential three step synthesis, using as the key step a radical reductive decarbonylation of 4-carboxy derivatives through their phenyl selenoesters 2.

Application of (+)-(1S,2S)-2-amino-1-phenylpropan-1,3-diol in the formal total synthesis of carbapenems, novel 4-cyano-β-lactams and β-hydroxy aspartates

The imines derived from (+)-(1S,2S)-2-amino-1-phenylpropan-1,3-diol furnished cis-β-lactams stereoselectively on the Staudinger reaction. These homochiral cis-β-lactams were converted in to cis-β-lactams possessing aminol side chain at C-4. These aminols