- Copper(I)-mediated and microwave-assisted Caryl-O carboxylic coupling: Synthesis of benzopyranones and isolamellarin alkaloids
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(Chemical Equation Presented) A simple and highly effective C-O carboxylic coupling reaction catalyzed by copper(I) salts has been developed to synthesize benzopyranones. The reaction of various 2-halobiarylcarboxylic acids was examined using m
- Thasana, Nopporn,Worayuthakarn, Rattana,Kradanrat, Phithakpong,Hohn, Elliot,Young, Lauren,Ruchirawat, Somsak
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- General and practical carboxyl-group-directed remote C-H oxygenation reactions of arenes
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Two methods for remote aromatic C-H oxygenation reactions, have been developed. Method1, the Cu-catalyzed oxygenation reaction, is highly efficient for cyclization of electron-neutral and electron-rich biaryl carboxylic acids into 3,4-benzocoumarins. Method2, the K2S2O 8-mediated oxygenation reaction, is more general and practical for cyclization of substrates with electron-donating and -withdrawing groups (see scheme). Copyright
- Wang, Yang,Gulevich, Anton V.,Gevorgyan, Vladimir
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p. 15836 - 15840
(2014/04/03)
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