The present invention relates to a process for the preparation of solid acylphosphine oxides by converting an acylphosphine oxide which is in the form of a melt or in dispersed form into the solid state of aggregation with mechanical stress, shearing/internal agitation of the melt.
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(2008/06/13)
Photo-curable reparative material for dental use
A photocurable dental restorative comprising (i) 100 parts by weight of a polymerizable monomer, (ii) 0.01 to 5 parts by weight of a photopolymerization initiator of acylphosphine oxide, and (iii) 200 to 1900 parts by weight of an inorganic filler, wherein the inorganic filler (iii) is a mixed filler of: (A) irregular-shaped inorganic particles having an average particle size of not smaller than 0.1 μm but smaller than 1 μm; (B) spherical inorganic particles having an average primary particle size of not smaller than 0.1 μm but not larger than 5 μm; and (C) fine inorganic particles having an average primary particle size of not larger than 0.1 μm; which are so blended as to satisfy the following mass ratios {circle over (1)} to {circle over (3)}: mA/(mB+mC)=0.2 to 3??{circle over (1)} mB/(mB+mC)=0.5 to 0.99??{circle over (2)} mC/(mB+mC)=0.01 to 0.5??{circle over (3)} where mA, mB and mC are masses of the inorganic particles (A) to (C). The restorative features excellent handling property, and makes it possible to obtain a cured product having a high fracture toughness and excellently glossy surface.
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(2008/06/13)
Imaging thrombus with glycoprotein llb/llla antagonists
This invention relates to a method of using a radiolabeled small molecule antagonist of the platelet IIb/IIIa receptor for the diagnosis of arterial and venous thrombi.
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(2008/06/13)
Use of small molecule radioligands to discover inhibitors of amyloid-beta peptide production and for diagnostic imaging
This invention relates to a method of using radiolabelled and/or radiopharmaceutical small molecule inhibitors of beta-amyloid peptide production for the diagnosis of neurological and other disorders involving APP processing and beta-amyloid production. Furthermore, radiolabelled small molecule inhibitors identified by the methods of the present invention would be useful in the diagnosis of neurological disorders, such as Alzheimer's disease, which involve elevated levels of Aβ peptides.
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(2008/06/13)
Molecular complex compounds of acylphosphine oxide and α-hydroxy ketones as photoinitiators
Molecular complex compounds comprising a mono-, bis- or trisacylphosphine oxide compound with an α-hydroxy ketone compound are suitable as photoinitiators for the photopolymerization of free-radically polymerizable compounds.
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(2008/06/13)
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