- 1-Substituted-1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-alkyloximes as novel orally active and long-lasting muscarinic cholinergic agonists
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Our previous attempts to design muscarinic agonists related to arecoline with the prerequisites for clinical use were successful with the discovery of 1,2,5,6-tetrahydropyridine-3-carboxaldehyde-O-methyloxime hydrochloride, RU 35963, and structurally rela
- Toja, E,Bonetti, C,Butti, A,Hunt, P,Fortin, M,et al.
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p. 519 - 526
(2007/10/02)
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- Carbamate derivatives of the oxime of 1,2,5,6-tetrahydropyridin-3-carboxaldehyde, their use as medicaments and compositions containing them
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Compounds useful in the treatment of patients suffering from senile dementia, Alzheimer's disease, or memory defects, of the formula STR1 in which R' represents hydrogen, a linear, branched or cyclic alkyl, alkenyl or alkynyl, containing up to 8 carbon at
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