145096-25-9Relevant articles and documents
PYRIDYL SUBSTITUTED BENZOTHIAZOLE COMPOUNDS WHICH HAVE USEFUL PHARMACEUTICAL UTILITY
-
, (2008/06/13)
A benzothiazole derivative or a pharmacologically acceptable salt thereof which is useful as a preventive or therapeutic agent for diseases on which functions of suppressing leukotrienes and thromboxanes production are effective. A benzothiazole derivativ
Novel dual inhibitors of 5-lipoxygenase and thromboxane A2 synthetase: Synthesis and structure-activity relationships of 3-pyridylmethyl-substituted 2-amino-6-hydroxybenzothiazole derivatives
Hibi,Okamoto,Tagami,Numata,Kobayashi,Shinoda,Kawahara,Murakami,Oketani,Inoue,Shibata,Yamatsu
, p. 3062 - 3070 (2007/10/02)
As part of our search for novel antiinflammatory drug candidates, we have designed and synthesized a series of 3-pyridylmethyl-substituted 2-amino-6- hydroxybenzothiazoles. Introduction of a 3-pyridylmethyl group into the 2- amino group (type-A) or the be