- A facile synthesis of tetrahydroimidazo[1,2-a]pyridines and tetrahydrobenzo[b]imidazo[1,2,3-ij][1,8]naphthyridines through NHC-catalyzed cascade annulations
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A new efficient approach for the synthesis of tetrahydroimidazo[1,2-a] pyridines and tetrahydrobenzo[b]imidazo[1,2,3-ij][1,8]naphthyridines with biological significance was successfully developed through a NHC-catalyzed cascade C-C bond and C-N bond formation process. This new alternative approach for the assembly of these multi-functionalized nitrogen bridgehead-fused heterocycles features mild conditions, moderate to high yields and operational simplicity. The Royal Society of Chemistry 2013.
- Yao, Changsheng,Jiao, Weihui,Xiao, Zhaoxin,Xie, Yuanwei,Li, Tuanjie,Wang, Xiangshan,Liu, Rui,Yu, Chenxia
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p. 10801 - 10805
(2013/09/02)
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