1451095-00-3Relevant articles and documents
An efficient one-pot synthesis of novel isatin-based 2-amino thiazol-4-one conjugates using MgO nanoparticles in aqueous media
Baharfar, Robabeh,Shariati, Narges
, p. 413 - 419 (2014)
An efficient and green approach for the preparation of novel isatin-based conjugates with 2-amino thiazol-4-ones is described by the one-pot reaction of isatin derivatives, rhodanine, and secondary amines in the presence of magnesium oxide nanoparticles as a heterogeneous catalyst in water as a green solvent at room temperature. This new protocol provides products in good yields and short reaction times using a simple work-up procedure. The structure of one representative compound has been confirmed by X-ray single-crystal analysis.
γ-Aminobutyric acid hydrochloride supported on superparamagnetic γ-Fe2O3@SiO2 as a novel heterogeneous nanocatalyst for the synthesis of 2-amino-5-alkylidene-thiazol-4-one derivatives
Mohammadi, Hadi,Shaterian, Hamid Reza
, p. 479 - 492 (2019/02/17)
γ-Aminobutyric acid hydrochloride immobilized on superparamagnetic γ-Fe2O3@SiO2 nanoparticles as a novel heterogeneous nanocatalyst was prepared for the first times. It was characterized by several techniques such as XRD, FT-IR, VSM, FE-SEM, EDS, and TGA analysis. The heterogeneous nanocatalyst was used for a convenient, mild, and one-pot efficient three-component preparation of 2-amino-5-alkylidene-thiazol-4-one derivatives under green conditions at room temperature. The main advantage of the method is easily recovery of the stable nanocatalyst by an external magnet from the reaction mixture.
Synthesis of molecular scaffolds assimilating both indolinone and thiazolidinone moieties under environmentally benevolent conditions
Ray, Suman,Mukhopadhyay, Chhanda
, p. 5078 - 5082 (2013/09/02)
A chromatography free synthesis of 2-amino-5-isatinylidenethiazol-4-ones from rhodanine, isatin, and amine under environmentally benevolent conditions is reported for the first time. The molecular scaffolds assimilating both indolinone and thiazolidinone moieties are reported to have great biological significance.
