Asymmetric Ring Transformation of meso-7-Substituted Bicyclooctanones into Chiral Bicyclooctene Derivatives
Asymmetric ring transformation of meso-7-(2-oxoalkyl)bicyclooctan-3-ones into chiral bicyclooct-2-ene derivatives is accomplished by treatment with chiral cyclic (six- or seven-mebered ring) 1,2-diols-BF3-Et2O.