145317-11-9 Usage
Uses
Used in Pharmaceutical Industry:
1H-Pyrrole-2,5-dione, 3-[8-(aMinoMethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-Methyl-1H-indol-3-yl)-, Monohy is used as a potential therapeutic agent for various medical conditions. Its unique molecular structure may allow it to interact with specific biological targets, such as enzymes or receptors, to modulate their activity and provide therapeutic benefits.
Used in Chemical Research:
In the field of chemical research, 1H-Pyrrole-2,5-dione, 3-[8-(aMinoMethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-Methyl-1H-indol-3-yl)-, Monohy can serve as a starting material or a key intermediate for the synthesis of other complex organic compounds. Its unique structure may be exploited to develop novel chemical entities with potential applications in various industries.
Used in Material Science:
The unique molecular structure of 1H-Pyrrole-2,5-dione, 3-[8-(aMinoMethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-Methyl-1H-indol-3-yl)-, Monohy may also find applications in the field of material science. Its properties, such as its ability to form specific interactions with other molecules or its potential to self-assemble into organized structures, could be harnessed to develop new materials with unique properties and applications.
References
1) Wilkinson et al. (1993), Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C; Biochem. J., 294 335
2) Niu et al. (2011), PKCε regulates contraction-stimulated GLUT4 traffic in skeletal muscle cells; J. Cell Physiol., 226 173
3) Jimenez-Lopez et al. (2005), Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells; J. Pharmacol. Exp. Ther., 312 998
4) Levy et al. (2015), A small-molecule screen for enhanced homing of systemically infused cells; Cell Rep., 10 1261
Check Digit Verification of cas no
The CAS Registry Mumber 145317-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,3,1 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 145317-11:
(8*1)+(7*4)+(6*5)+(5*3)+(4*1)+(3*7)+(2*1)+(1*1)=109
109 % 10 = 9
So 145317-11-9 is a valid CAS Registry Number.
145317-11-9Relevant articles and documents
4-?3-indolyl!-1H-pyrrolone
-
, (2008/06/13)
A compound of the formula STR1 wherein R is hydrogen or hydroxy, R1 and R2 taken together are a group of the formula --(CH2)m -- and R7 is hydrogen or R1 and R7 taken together are a group of the formula --(CH2)n -- and R2 is hydrogen; R3 is an aryl or aromatic heterocyclic group; R4, R5 and R6 each independently are hydrogen, halogen, alkyl, hydroxy, alkoxy, haloalkyl, nitro, amino, acylamino, alkylthio, alkylsulfinyl or alkylsulfonyl; R8 is a group of the formula --(CH2)p --R9 or --(CH2)q --R10 ; R9 is hydrogen, alkylcarbonyl, aminoalkylcarbonyl, cyano, amidino, alkoxycarbonyl, aryloxycarbonyl, alkylsulfonyl, aminocarbonyl or aminothiocarbonyl; R10 is hydroxy, alkoxy, halogen, amino, monoalkylamino, dialkylamino, trialkylamino, azido, acylamino, alkylsulfonylamino, a 5- or 6-membered saturated nitrogen-containing heterocycle; X and Y are oxygen; Z is CH; m, p and q are, independently, an integer from 0 to 5, and n an integer from 1 to 5, as well as pharmaceutically acceptable salts thereof which are useful in the control of inflammatory, immunological, oncological, bronchopulmonary or cardiovascular disorders.
