145326-64-3Relevant articles and documents
INDOLO-SUBSTITUTED-PIPERIDINE COMPOUNDS AS ESTROGEN RECEPTOR DEGRADING AGENT
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Paragraph 0179, (2019/02/09)
Disclosed is a new indole compound, in particular, the compound as shown in formula (I), and a preparation method, pharmaceutical composition and use thereof as an estrogen receptor down-regulator in preparing drugs for treating estrogen receptor-positive breast cancer.
Studies on the preparation of 2-indolyl triflates and related compounds
Conway,Gribble
, p. 2987 - 2995 (2007/10/02)
Upon treatment with trifluoromethanesulfonic acid anhydride (triflic anhydride), oxindole (4) is converted into 1-(trifluoromethanesulfonyl)indol-2-yl trifluoromethanesulfonate (10) in 70% yield. Some attempted reactions of 1-(trifluoromethanesulfonyl)indole (13), conveniently prepared by treating indole (12) with n-butyllithium and triflic anhydride, are described.