Synthesis of Chiral 5-Substituted 2-Pyrrolidones, Metabolites of the Antipsychotic Benzamides Remoxipride and Raclopride
Three of the major human metabolites of remoxipride (1) and raclopride (6) have been synthesized in optically active form.Starting from L-pyroglutamic acid, the two pyrrolidones (+)-(5S)-5-(aminomethyl)-2-pyrrolidone (10) and (+)-(5S)-5-(aminomethyl)-1-et
Gawell, Lars,Stroem, Peter,Hoegberg, Thomas
p. 981 - 984
(2007/10/02)
More Articles about upstream products of 145351-57-1