1,3-Dioxolanylpurine nucleosides (2R,4R) and (2R,4S) with selective anti- HIV-1 activity in human lymphocytes
In order to study the structure-activity relationships of dioxolane nucleosides as potential anti-HIV-1 agents, various enantiomers of pure dioxolanylpurine nucleosides were synthesized and evaluated against HIV-1 in human peripheral blood mononuclear cel