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[[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid is a complex phosphorylated nucleotide analog with a unique chemical structure that incorporates elements such as oxygen, hydrogen, phosphorus, sulfur, nitrogen, and fluorine. [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid has garnered significant interest in pharmaceutical and medical research due to its potential applications in antiviral and anticancer therapies.

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  • Triphosphoric acid,P-[[(2R,5S)-5-(4-amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolan-2-yl]methyl]ester

    Cas No: 145819-92-7

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  • [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid

    Cas No: 145819-92-7

  • USD $ 10.0-10.0 / Milligram

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  • 145819-92-7 Structure
  • Basic information

    1. Product Name: [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid
    2. Synonyms: [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid;5-fluoro-1-(2-hydroxymethyl)-1,3-oxathiolane-5-yl-cytidine-5'-triphosphate
    3. CAS NO:145819-92-7
    4. Molecular Formula: C8H13FN3O12P3S
    5. Molecular Weight: 487.19
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 145819-92-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 2.08g/cm3
    6. Refractive Index: 1.651
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid(145819-92-7)
    11. EPA Substance Registry System: [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid(145819-92-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 145819-92-7(Hazardous Substances Data)

145819-92-7 Usage

Uses

Used in Antiviral Applications:
[[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid is used as an antiviral agent for its ability to inhibit viral DNA polymerases, thereby disrupting the replication process of various viruses.
Used in Cancer Treatment:
In the field of oncology, [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid is being studied for its potential as a cancer treatment. Its capacity to inhibit DNA synthesis makes it a promising candidate for targeting rapidly dividing cancer cells.
Used in Pharmaceutical Research:
Due to its complex nature and the variety of elements it contains, [[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphonic acid is also used in pharmaceutical research to explore its potential in the development of new drugs and therapies for various diseases.
Used in Medical Research:
[[[(2R,5S)-5-(4-amino-5-fluoro-2,6-dioxo-3H-pyrimidin-1-yl)-1,3-oxathi olan-2-yl]methyl-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxyphosphon ic acid's unique properties and potential applications have made it a subject of interest in medical research, where it is being investigated for its possible role in treating a range of conditions, including viral infections and cancer.

Check Digit Verification of cas no

The CAS Registry Mumber 145819-92-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,8,1 and 9 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 145819-92:
(8*1)+(7*4)+(6*5)+(5*8)+(4*1)+(3*9)+(2*9)+(1*2)=157
157 % 10 = 7
So 145819-92-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H13FN3O12P3S/c9-5-6(10)11-8(14)12(7(5)13)3-2-28-4(22-3)1-25(15,16)23-27(20,21)24-26(17,18)19/h3-4H,1-2,10H2,(H,11,14)(H,15,16)(H,20,21)(H2,17,18,19)/t3-,4+/m0/s1

145819-92-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name [(2R,5S)-5-(6-amino-5-fluoro-2,4-dioxo-1H-pyrimidin-3-yl)-1,3-oxathiolan-2-yl]methyl-[hydroxy(phosphonooxy)phosphoryl]oxyphosphinic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:145819-92-7 SDS

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