146059-77-0 Usage
Uses
Used in Pharmaceutical Industry:
5-(HydroxyMethyl)piperidin-2-one is used as a building block for the synthesis of various drugs, including antihistamines, antipsychotics, and anti-inflammatory agents. Its incorporation into these medications aids in the treatment of allergies, mental health disorders, and inflammatory conditions, respectively.
Used in Agrochemical Industry:
5-HMP is also utilized as a building block in the preparation of agrochemicals, contributing to the development of pesticides and other agricultural chemicals that protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
As a key intermediate in organic synthesis, 5-(HydroxyMethyl)piperidin-2-one is employed in the creation of bioactive molecules. Its unique reactivity allows for the formation of new compounds with potential applications in various fields, including medicine and materials science.
Used in Research and Development:
5-HMP serves as a valuable tool in research and development, where its properties are explored for the discovery and optimization of new chemical entities. Its presence in the synthesis process can lead to innovative solutions in drug development and other areas of chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 146059-77-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,0,5 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 146059-77:
(8*1)+(7*4)+(6*6)+(5*0)+(4*5)+(3*9)+(2*7)+(1*7)=140
140 % 10 = 0
So 146059-77-0 is a valid CAS Registry Number.
146059-77-0Relevant articles and documents
SUBSTITUTED PYRIDOPYRAZINES AS SYK INHIBITORS
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Page/Page column 42, (2014/06/24)
The present invention relates to pyridopyrazine compounds of formula (I), pharmaceutical compositions thereof and methods of use therefore, wherein R1, R2, R3, L, m, p and W are as defined in the specification.
Synthesis of (±)-strychnofoline via a highly convergent selective annulation reaction
Lerchner, Andreas,Carreira, Erick M.
, p. 8208 - 8219 (2007/10/03)
Studies aimed at preparing (±)-strychnofoline by total synthesis are detailed. The route described makes use of a recently developed MgI 2-mediated ring-expansion reaction of spiro[cyclopropan-1,3′- oxindole] with a cyclic disubstituted aldimin
First total synthesis of (±)-strychnofoline via a highly selective ring-expansion reaction
Lerchner, Andreas,Carreira, Erick M.
, p. 14826 - 14827 (2007/10/03)
An efficient synthesis of the antitumor alkaloid (±)-strychnofoline is documented. Key to the development of the highly convergent strategy delineated is the coupling of a cyclic imine with spiro[cyclopropan-1,3'-oxindole], which takes place in a highly d
2-piperidones as intermediates for 5-deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acids
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, (2008/06/13)
4-Deaza-10-oxo- and 5-deaza-10-thio-5,6,7,8-tetrahydrofolic acid derivatives are provided as agents useful for treatment susceptible neoplasms in mammals. Pharmaceutical formulations and intermediates are also provided.
