Disclosed are benzothiophene and thienothiophene derivatives useful for inhibiting urokinase activity.
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(2008/06/13)
Fluorine as an ortho-directing group in aromatic metalation: A two step preparation of substituted benzo[b] thiophene-2-carboxylates
A simple 2-step synthesis of B-ring substituted benzo[b]thiophene-2-carboxylates from aryl fluorides has been developed. The route involves a selective lithiation ortho to fluorine, followed by formylation, and subsequently, displacement of fluorine with
Bridges, Alexander J.,Lee, Arthur,Maduakor, Emmanuel C.,Eric Schwartz
p. 7499 - 7502
(2007/10/02)
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