14617-95-9

Basic information

• Product Name: ANISYLN-BUTYRATE
• Synonyms: ANISYLN-BUTYRATE;Butanoic acid 4-methoxyphenyl ester;Butanoic acid p-methoxyphenyl ester
• CAS NO: 14617-95-9
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 208.2
• Mol File: 14617-95-9.mol

Chemical Properties

• Boiling Point: 267°C (estimate)
• Flash Point: 112.6°C
• Appearance: /
• Density: 1.0989 (rough estimate)
• Vapor Pressure: 0.0038mmHg at 25°C
• Refractive Index: 1.5040 (estimate)
• CAS DataBase Reference: ANISYLN-BUTYRATE(CAS DataBase Reference)
• NIST Chemistry Reference: ANISYLN-BUTYRATE(14617-95-9)
• EPA Substance Registry System: ANISYLN-BUTYRATE(14617-95-9)

Safety Data

• Hazardous Substances Data: 14617-95-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14O3/c1-3-4-11(12)14-10-7-5-9(13-2)6-8-10/h5-8H,3-4H2,1-2H3

Upstream product

• 150-76-5 4-methoxy-phenol 
• 107-92-6 butyric acid 
• 556812-41-0 4-methoxy-2-(trimethylsilyl)phenyl triflate 

Downstream Products

• 138854-48-5 2-(1,1-dimethyl-2,3-epoxypropyl)-4-methoxyphenyl n-butyrate 
• 150-76-5 4-methoxy-phenol 

Relevant articles and documents

Activity and specificity studies of the new thermostable esterase EstDZ2

In this paper, we study the activity and specificity of EstDZ2, a new thermostable carboxyl esterase of unknown function, which was isolated from a metagenome library from a Russian hot spring. The biocatalytic reaction employing EstDZ2 proved to be an efficient method for the hydrolysis of aryl p-, o- or m-substituted esters of butyric acid and esters of secondary alcohols. Docking studies revealed structural features of the enzyme that led to activity differences among the different substrates.

The insertion of arynes into the O-H bond of aliphatic carboxylic acids

The insertion of arynes into the O-H bond of aliphatic carboxylic acids promoted by sodium carboxylates is described. The reactions led to the formation of aryl carboxylates in good yields with good chemoselectivities under mild conditions.

A novel aromatic carbocation-based coupling reagent for esterification and amidation reactions

A novel tropylium-based coupling reagent has been developed to facilitate the synthesis of a series of esters, amides, lactones and peptides under mild reaction conditions. Remarkably, this reagent can be used in catalytic amounts in conjunction with a sacrificial reagent, offering a new and efficient method for nucleophilic coupling reactions of carboxylic acids.

Development of 2,3-Dihydro-6-(3-phenoxypropyl)-2-(2-phenylethyl)-5-benzofuranol (L-670,630) as a Potent and Orally Active Inhibitor of 5-Lipoxygenase

Leukotrienes are potent biological mediators of allergic and antiinflammatory diseases and are derived from arachidonic acid through the action of the 5-lipoxygenase.In this study, the syntheses and comparative biological activities of three series of 2,3-dihydro-2,6-disubstituted-5-benzofuranols with various substituents on position 3 are described.Compounds from each series were evaluated for their ability to inhibit the production of leukotriene B4 (LTB4) in human peripheral blood polymorphonuclear (PMN) leukocytes and the 5-lipoxygenase reaction in cell-free preparations from rat PMN leukocytes.The structure-activity relationships of each series in vitro and in vivo are presented.The bioavailability, metabolism, and toxicity profile of each series are discussed.The series with no substituent at position 3 was the most potent and among the compounds in that series 2,3-dihydro-6-(3-phenoxypropyl)2-(2-phenylethyl)-5-benzofuranol (46, L-670,630) was chosen for further development.

Electrochemical generation and reactions of acyloxytriphenylphosphonium ions

Constant-current electrolysis, in an undivided cell, of Ph3P in the presence of a carboxylic acid in CH2Cl2 containing 2,6-lutidinium perchlorate as the supporting electrolyte was shown to generate the corresponding acyloxyphosphonium ion, Ph3P+-OCOR, which was converted in situ to esters, amides, and β-lactams under mild conditions.