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3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 146426-54-2 Structure
  • Basic information

    1. Product Name: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid
    2. Synonyms: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid
    3. CAS NO:146426-54-2
    4. Molecular Formula: C10H11N5O5
    5. Molecular Weight:
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 146426-54-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid(146426-54-2)
    11. EPA Substance Registry System: 3-azido-1,2,3-trideoxy-1-(3,4-dihydro-5-Methyl-2,4-dioxo-1(2H)-pyriMidinyl)-D-erythro-Pentofuranuronic acid(146426-54-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 146426-54-2(Hazardous Substances Data)

146426-54-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 146426-54-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,4,2 and 6 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 146426-54:
(8*1)+(7*4)+(6*6)+(5*4)+(4*2)+(3*6)+(2*5)+(1*4)=132
132 % 10 = 2
So 146426-54-2 is a valid CAS Registry Number.

146426-54-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 3'-azido-3'-deoxy-thymidine-5'-carboxylic acid

1.2 Other means of identification

Product number -
Other names 3'-azido-thymidine-5'-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146426-54-2 SDS

146426-54-2Relevant articles and documents

Chimeric (α-amino acid + nucleoside-β-amino acid)n peptide oligomers show sequence specific DNA/RNA recognition

Gogoi, Khirud,Kumar, Vaijayanti A.

, p. 706 - 708 (2008)

An α/β-peptide backbone oligonucleotide comprising natural α-amino acids alternating with a β-amino acid component derived from thymidine sequence specifically recognizes and binds to deoxy- and ribo-oligoadenylates in triplex mode. The Royal Society of Chemistry.

An Entry of the Chemoselective Sulfo-Click Reaction into the Sphere of Nucleic Acids

Clavé, Guillaume,Dursun, Enes,Smietana, Michael,Vasseur, Jean-Jacques

, (2020)

We report here the first example of a sulfo-click conjugation reaction to be applied to modified nucleosides. The reaction, which proceeds rapidly (k ~2.0 × 10-1 M-1 s-1 at 25 °C) under aqueous biocompatible conditions in

Ruthenium tetraoxide catalyzed oxidation of nucleosides: A facile synthesis of 5'-carboxylic acid derivatives

Varma,Hogan

, p. 7719 - 7720 (1992)

Purine and pyrimidine nucleosides have been oxidized to the corresponding 5'-carboxylic acids using potassium persulfate and ruthenium trichloride under basic conditions. The method provides easy access to nucleosides bearing 3'-amino and 5'-carboxylic acid functionalities from 3'-azido compounds as exemplified by oxidation of AZT followed by reduction of the acid.

Nucleoside derived amino acids (NDA) in foldamer chemistry: synthesis and conformational studies of homooligomers of modified AZT

Chandrasekhar,Pavan Kumar Reddy,Udaya Kiran,Nagesh,Jagadeesh

, p. 2969 - 2973 (2008)

Homo short-oligomers of a novel trans-β-amino acid derived from AZT were synthesized and characterized. These adopt right-handed helical turns with their bases positioned systematically along the helix axis. These studies open up new possibilities for synthesizing nucleoside derived functional foldamers.

Novel helical foldamers: Organized heterogeneous backbone folding in 1:1 α/nucleoside-derived-β-amino acid sequences

Chandrasekhar, Srivari,Kiranmai, Nayani,Kiran, Marelli Udaya,Devi, Ambure Sharada,Reddy, Gangireddy Pavan Kumar,Idris, Mohammed,Jagadeesh, Bharatam

supporting information; experimental part, p. 6962 - 6964 (2010/11/03)

Secondary structural conformation of hybrid oligo-peptides comprised of 1:1 alternating Nucleoside Derived β-Amino acid (NDA) and l-amino acid residues has been reported. The studies reveal that the NDA residues organize the heterogeneous backbone featuri

Synthesis of aminodisaccharide-nucleoside conjugates for RNA binding

Cai, Li,Li, Qin,Ren, Bo,Yang, Zhen-Jun,Zhang, Liang-Ren,Zhang, Li-He

, p. 8135 - 8144 (2008/02/08)

Two types of aminodisaccharide-nucleoside conjugates were synthesized by the condensation of azidodisaccharide and nucleoside using aliphatic diamine as a linker. The corresponding azidodisaccharides could be yielded from neamine in good yield. The bindin

Synthesis of DNA analogues with novel carboxamidomethyl phosphonamide and glycinamide internucleoside linkages

Efimov,Buryakova,Chakhmakhcheva

, p. 1013 - 1018 (2007/10/03)

Thymidine oligonucleotide analogues with phosphodiester bonds fully substituted by carboxamidomethyl phosphonamide, or glycinamide linkages were synthesized on a solid support, and their hybridization properties toward DNA and RNA targets were determined by Tm analysis.

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