The synthesis and anti-inflammatory properties of a new sulindac analogue synthesized from natural safrole
The synthesis of the new sulindac (3) analogue (Z)-5,6-methylenedioxy-2- methyl-1-(p-methylsulfinylbenzylidene)-3-indenyl acetic acid (1) from natural safrole (2), an abundant natural product occurring as the principal chemical constituent of Sassafraz oi