146621-66-1

Basic information

• Product Name: pirbuterol
• Synonyms: 2,6-Pyridinedimethanol, α6-[[(1,1-dimethylethyl)amino]methyl]-3-hydroxy-, (+)-
• CAS NO: 146621-66-1
• Molecular Formula: C12H20 N2 O3
• Molecular Weight: 240.3
• Mol File: 146621-66-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: pirbuterol(CAS DataBase Reference)
• NIST Chemistry Reference: pirbuterol(146621-66-1)
• EPA Substance Registry System: pirbuterol(146621-66-1)

Safety Data

• Hazardous Substances Data: 146621-66-1(Hazardous Substances Data)

Relevant articles and documents

Combined doses

The present invention discloses a method and a pharmaceutical dry powder combined dose for the prophylaxis or treatment of a respiratory disorder in a mammalian host by inhalation of a metered dry powder combined dose of finely divided dry medication powders. At least one dry powder medicament is selected from a first group of bronchodilating medicaments and at least one dry powder medicament from a second group of anti-inflammatory medicaments. A metered dry powder medicinal combined dose comprising separately metered deposits of medicinally suitable quantities of each of the selected medicaments is prepared, in which the sum of the metered deposits constitutes the metered quantities of powder of the combined dose and the medicinal combined dose is introduced into an adapted inhaler device for a generally simultaneous delivery of the medicinal combined dose during the course of a single inhalation by a user, such that the delivered medicinal combined dose is composed of a high proportion of mixed de-aggregated fine particles of the selected medicaments, whereby an desired therapeutic or treating effect to the user is achieved.

Antiinflammatory salts of piroxicam

Improved antiinflammatory salts of piroxicam with antidepressant doxepin, with bronchodilator pirbuterol or isoproterenol, with H2 -antagonist inhibitor 2-guanidino-4-(2-methyl-4-imidazolyl)thiazole, with pyridoxine, a member of the vitamin B6 complex, or with antihypertensive trimazosin.

2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate

The maleic acid salt of 2-phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin, its preparation and use as an intermediate for making 2-hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-t-butylaminoethyl)pyridine, an effective bronchodilator.

2-HYDROXYMETHYL-3-HYDROXY-6-(1-HYDROXY-2-AMINOETHYL)PYRIDINES

2-Hydroxymethyl-3-hydroxy-6-(1-hydroxy-2-aminoethyl)-pyridines and salts thereof, a novel class of β-adrenergic agonist bronchodilators in mammals, and 2-hydroxymethyl-3-benzyloxy-6-pyridinecarboxaldehyde a valuable intermediate in the preparation of the subject compounds.