14677-21-5Relevant articles and documents
The chemistry of α,β-ditosyloxy ketones: A new and convenient route to 4,5-diarylisoxazoles from α,β-chalcone ditosylates
Kamal, Raj,Sharma, Deepak,Wadhwa, Deepak,Prakash, Om
experimental part, p. 93 - 96 (2012/02/03)
The reaction of α,β-chalcone ditosylates with hydroxyl-amine hydrochloride under suitable conditions leads to a 1,2-aryl shift, thereby providing a new route to 4,5-disubstituted isoxazoles. Georg Thieme Verlag Stuttgart. New York.
The amine exchange/biaryl coupling sequence: A direct entry to the phenanthro[9,10-d]heterocyclic framework
Olivera, Roberto,SanMartin, Raul,Tellitu, Imanol,Domínguez, Esther
, p. 3021 - 3037 (2007/10/03)
Novel phenanthro[9,10-d]pyrimidines and phenanthro[9,10-d][1,2]oxazoles are regioselectively prepared by the application of a straightforward synthetic pathway, starting from new o,o′-dihalogenated and non-halogenated 4,5-diarylpyrimidines and 4,5-diaryli
A convenient one-pot preparative method for 4,5-diarylisoxazoles involving amine exchange reactions
Dominguez, Esther,Ibeas, Estibaliz,De Marigorta, Eduardo Martinez,Palacios, Jon Kepa,SanMartin, Raul
, p. 5435 - 5439 (2007/10/03)
4,5-Diarylisoxazoles 1 are efficiently prepared by submitting enaminones 2, readily obtained from deoxybenzoins 3, to oximation conditions. This conversion implies an uncommon amine group exchange reaction. Preparation of 4-isoxazolines 5 and ring-opening transformations to β-keto nitriles 4 and 1,3-amino alcohol derivatives 7 are also described.
