146859-53-2Relevant articles and documents
N-(PYRIDIN-2-YL)-SULFONAMIDE DERIVATIVES
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Page/Page column 30, (2008/06/13)
The present invention relates to novel compounds, to pharmaceutical compositions comprising the compounds described herein, their pharmaceutically acceptable salts, hydrates and solvates, as well as to the use of the compounds in medicine and for the prep
Vitronectin receptor antagonists
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, (2008/06/13)
Compounds of the formula (I) are disclosed which are vitronectin receptor antagonists and are useful in the treatment of osteoporosis: or a pharmaceutically acceptable salt thereof.
Triazolopyridines. 14. Substitution Reactions of 7-AminoTriazoloPyridines
Asensio, Amparo,Abarca, Belen,Jones, Gurnos,Hursthouse, Michael B.,Malik, K. M. Abdul
, p. 703 - 712 (2007/10/02)
Reaction between 7-aminotriazolopyridines 1 or 2 and sulphuric acid gives hydroxyalkylpyridines 3 and 4; bromination gives brominated pyridine 5 or triazolopyridine 6.The anions from 1 or 2 are ambient, acylating on N but alkylating on N or on C6; in the latter case triazolylalkenylcyanides 16 - 20 or the 6,6-dialkylated derivative 19 are obtained.An X-ray diffraction study has confirmed structure 19. Key Words: Aminotriazolopyridines; Ambident Anions; Alkylation/Acylation; Triazolylalkenyl Cyanides; X-ray Diffraction.