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1-cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenylpyrrolidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 146981-11-5 Structure
  • Basic information

    1. Product Name: 1-cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenylpyrrolidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
    2. Synonyms: 1-Cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenyl-1-pyrrolidinyl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 3-quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3-(methylamino)-3-phenyl-1-pyrrolidinyl]-4-oxo-
    3. CAS NO:146981-11-5
    4. Molecular Formula: C24H24FN3O3
    5. Molecular Weight: 421.4641
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 146981-11-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 639.8°C at 760 mmHg
    3. Flash Point: 340.7°C
    4. Appearance: N/A
    5. Density: 1.41g/cm3
    6. Vapor Pressure: 3.04E-17mmHg at 25°C
    7. Refractive Index: 1.687
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 1-cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenylpyrrolidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(CAS DataBase Reference)
    11. NIST Chemistry Reference: 1-cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenylpyrrolidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(146981-11-5)
    12. EPA Substance Registry System: 1-cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenylpyrrolidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid(146981-11-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 146981-11-5(Hazardous Substances Data)

146981-11-5 Usage

Quinoline ring

A core structure in the compound, consisting of a benzene ring fused with a nitrogen-containing pyridine ring, responsible for the antibiotic's activity.

Carboxylic acid group

A functional group (-COOH) attached to the quinoline ring, contributing to the compound's acidity and solubility.

Fluoro group

A fluorine atom (-F) attached to the quinoline ring, which can enhance the compound's potency and metabolic stability.

Methylamino substituent

A functional group (-NHCH3) attached to the pyrrolidine ring, which may influence the compound's binding affinity to its target enzymes.

Inhibition of bacterial DNA gyrase and topoisomerase IV

The primary mechanism of action for this antibiotic, which disrupts bacterial DNA replication and repair, leading to bacterial cell death.

Effectiveness against gram-negative bacteria

This compound is particularly effective against a wide range of bacterial infections caused by gram-negative bacteria due to its ability to penetrate their outer membrane and target essential enzymes.

Synthetic antibiotic

This compound is a synthetically produced member of the quinolone class of antibiotics, which are known for their broad-spectrum activity against various bacterial infections.

Check Digit Verification of cas no

The CAS Registry Mumber 146981-11-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,9,8 and 1 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 146981-11:
(8*1)+(7*4)+(6*6)+(5*9)+(4*8)+(3*1)+(2*1)+(1*1)=155
155 % 10 = 5
So 146981-11-5 is a valid CAS Registry Number.

146981-11-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-cyclopropyl-6-fluoro-7-[3-(methylamino)-3-phenylpyrrolidin-1-yl]-4-oxoquinoline-3-carboxylic acid

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:146981-11-5 SDS

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