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2-(4-Fluorophenoxy)-3-nitropyridine is a chemical compound characterized by the molecular formula C11H7FN2O3. It is a derivative of nitro pyridine with a fluorophenoxy group attached at the second position. The presence of a fluorine atom in the molecule endows it with unique chemical and physical properties, which are valuable in medicinal chemistry. The nitro group also allows for a variety of chemical reactions, facilitating the synthesis of diverse compounds for potential drug candidates.

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  • 147143-58-6 Structure
  • Basic information

    1. Product Name: 2-(4-FLUOROPHENOXY)-3-NITROPYRIDINE
    2. Synonyms: 2-(4-FLUOROPHENOXY)-3-NITROPYRIDINE;BUTTPARK 48\08-43;2-(4-Fluorophenoxy)-3-nitropyridine 97%;2-(4-Fluorophenoxy)-3-nitropyridine97%
    3. CAS NO:147143-58-6
    4. Molecular Formula: C11H7FN2O3
    5. Molecular Weight: 234.18
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 147143-58-6.mol
  • Chemical Properties

    1. Melting Point: 98 °C
    2. Boiling Point: 327.1 °C at 760 mmHg
    3. Flash Point: 151.6 °C
    4. Appearance: /
    5. Density: 1.383 g/cm3
    6. Vapor Pressure: 0.000394mmHg at 25°C
    7. Refractive Index: 1.592
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-(4-FLUOROPHENOXY)-3-NITROPYRIDINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(4-FLUOROPHENOXY)-3-NITROPYRIDINE(147143-58-6)
    12. EPA Substance Registry System: 2-(4-FLUOROPHENOXY)-3-NITROPYRIDINE(147143-58-6)
  • Safety Data

    1. Hazard Codes: T
    2. Statements: 20/21/22-36/37/38
    3. Safety Statements: 26-36/37/39
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: TOXIC
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 147143-58-6(Hazardous Substances Data)

147143-58-6 Usage

Uses

Used in Pharmaceutical Research and Development:
2-(4-Fluorophenoxy)-3-nitropyridine is utilized as an intermediate in the synthesis of various pharmaceutical drugs. Its unique properties, including the fluorine atom and the nitro group, make it a valuable component in the development of new drug molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(4-Fluorophenoxy)-3-nitropyridine is used as a building block for the design and synthesis of novel compounds with potential therapeutic applications. The fluorine atom can influence the pharmacokinetics and pharmacodynamics of the resulting compounds, while the nitro group provides opportunities for further chemical modifications.

Check Digit Verification of cas no

The CAS Registry Mumber 147143-58-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,1,4 and 3 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 147143-58:
(8*1)+(7*4)+(6*7)+(5*1)+(4*4)+(3*3)+(2*5)+(1*8)=126
126 % 10 = 6
So 147143-58-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H7FN2O3/c12-8-3-5-9(6-4-8)17-11-10(14(15)16)2-1-7-13-11/h1-7H

147143-58-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-FLUOROPHENOXY)-3-NITROPYRIDINE

1.2 Other means of identification

Product number -
Other names 2-(2-METHOXYPHENOXY)-5-(PIPERIDIN-1-YLSULFONYL)ANILINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147143-58-6 SDS

147143-58-6Downstream Products

147143-58-6Relevant articles and documents

PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF

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Page/Page column 82, (2010/10/20)

The present invention provides novel pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof, processes for the preparation thereof, and compositions comprising the same. The pyrrolo[2,3-c]pyridine derivatives or pharmaceutically acceptable salts thereof of the present invention have excellent proton pump inhibition effects and possess the ability to attain a reversible proton pump inhibitory effect.

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