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2-bromo-3-4-difluoropropiophenone is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 147214-39-9 Structure
  • Basic information

    1. Product Name: 2-bromo-3-4-difluoropropiophenone
    2. Synonyms: 2-bromo-3-4-difluoropropiophenone;2-bromo-1-(3,4-difluorophenyl)propan-1-one
    3. CAS NO:147214-39-9
    4. Molecular Formula: C8H5BrF2O
    5. Molecular Weight: 249.0521
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 147214-39-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 269.3 °C at 760 mmHg
    3. Flash Point: 116.6 °C
    4. Appearance: /
    5. Density: 1.561 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-bromo-3-4-difluoropropiophenone(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-bromo-3-4-difluoropropiophenone(147214-39-9)
    11. EPA Substance Registry System: 2-bromo-3-4-difluoropropiophenone(147214-39-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 147214-39-9(Hazardous Substances Data)

147214-39-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 147214-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,2,1 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 147214-39:
(8*1)+(7*4)+(6*7)+(5*2)+(4*1)+(3*4)+(2*3)+(1*9)=119
119 % 10 = 9
So 147214-39-9 is a valid CAS Registry Number.

147214-39-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-bromo-1-(3,4-difluorophenyl)propan-1-one

1.2 Other means of identification

Product number -
Other names 1-Propanone,2-bromo-1-(3,4-difluorophenyl)

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:147214-39-9 SDS

147214-39-9Downstream Products

147214-39-9Relevant articles and documents

Novel Imidazole Derivatives Useful for the Treatment of Arthritis

-

Page/Page column 14, (2012/12/13)

The present invention provides compounds of the formula below: where A, X and R1-R6 are as described herein, a pharmaceutical salt thereof, and a pharmaceutical composition containing this compound; methods of treating pain associated with osteoarthritis using one of the compounds or a pharmaceutically acceptable salt thereof, and processes for preparing the compounds.

MONOAM1NE REUPTAKE INHIBITORS

-

Page/Page column 69, (2010/11/04)

The invention provides bupropion analogue compounds capable of inhibiting the reuptake of one or more monoamines. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine,and serotonin. Such compounds may be used to treat conditions that are responsive to inhibition of the reuptake of monoamines, including addiction, depression, and obesity

Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction

Carroll, F. Ivy,Blough, Bruce E.,Abraham, Philip,Mills, Andrew C.,Holleman, J. Ashley,Wolckenhauer, Scott A.,Decker, Ann M.,Landavazo, Antonio,McElroy, K. Timothy,Navarro, Hernán A.,Gatch, Michael B.,Forster, Michael J.

supporting information; experimental part, p. 6768 - 6781 (2010/04/06)

A series of bupropion (1a) analogues (1b-1ff) were synthesized, and their in vitro and in vivo pharmacological properties evaluated with the goal of developing a 1a analogue that had better properties for treating addictions. Their in vitro pharmacological properties were examined by [3H] dopamine ([3H]DA), [3H]serotonin ([3H]5HT), and [3H]norepinephrine ([3H]NE) uptake inhibition studies, and by binding studies at the dopamine, serotonin, and norepinephrine transporters using [125I]RTI-55 in cloned transporters. Several analogues showed increased [3H]DAuptake inhibition with reduced or little change in [3H]5HT and [3H]NE uptake inhibition relative to bupropion. Thirty-five analogues were evaluated in a 1 h locomotor activity observation test and 32 in an 8 h locomotor activity observation test and compared to the locomotor activity of cocaine. Twenty-four analogues were evaluated for generalization to cocaine drug discrimination after i.p. administration, and twelve analogues were tested in a time course cocaine discrimination study using oral administration. 2-(N-Cyclopropylamino)-3- chloropropiophenone (1x) had the most favorable in vitro efficacy and in vivo pharmacological profile for an indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction. 2009 American Chemical Society.

Arylmorpholine, preparation and use

-

, (2008/06/13)

A method for the treatment of depression in a human being, the method comprising administering to the human being an antidepressant effective amount of a compound of the following formula STR1 or a pharmaceutically acceptable salt thereof, wherein R and R

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